Drugs of abuse have strong addictive properties which cause you trouble quitting drugs once you abuse them. Once the drug effects go off, you will have irritation and jitters, leading to loss of self-control and cravings for drugs, and consequently ending up with obsessive and compulsive abuses.

If you further continue abuse, you will have paranoia and other psychotic symptoms, which may cause more serious secondary crimes, involving violence and destruction, such as mayhem, murder, arson and robbery, resulting in a catastrophe.